This advanced clinical reference provides a comprehensive comparison of antidepressant medications, including SSRIs, SNRIs, TCAs, MAOIs, and atypical agents. It highlights each drug’s mechanism of action, half-life, dosage ranges, and key clinical features. Special focus is given to efficacy across depression subtypes, comorbid conditions, and side effect profiles such as weight gain, sedation, or sexual dysfunction. The guide also reviews pharmacokinetics, drug–drug interactions, and metabolism pathways.
Clinical selection tips help clinicians choose appropriate therapies for patients with anxiety, chronic pain, or treatment-resistant depression. Considerations for special populations—including adolescents, pregnant women, and elderly patients—are discussed. Combination strategies and augmentation options are also included for difficult-to-treat cases. Designed as a visual and practical tool, this reference supports evidence-based prescribing and enhances treatment decision-making for healthcare providers.