Medications for substance use disorders (SUDs) play a critical role in recovery, relapse prevention, and harm reduction—but their safety and efficacy depend on vigilant monitoring. Whether using buprenorphine for opioid use disorder, disulfiram or naltrexone for alcohol dependence, or off-label agents like topiramate, psychiatric NPs must follow evidence-based protocols to ensure therapeutic success and minimize complications.
This section provides a comprehensive overview of lab tests, vitals, liver function panels, and urine drug screens commonly required when managing patients on SUD pharmacotherapies. It also highlights monitoring frequency, medication interactions, and signs of nonadherence or diversion. With structured oversight, these medications can be powerful allies in long-term recovery, restoring function and saving lives.