Not all psychiatric symptoms respond to first-line treatments alone. That’s where miscellaneous and augmentation medications come in—the unsung support crew that enhances or complements primary therapies. These include agents like buspirone for anxiety, modafinil for fatigue or cognitive dulling, prazosin for PTSD-related nightmares, and low-dose antipsychotics or thyroid hormones used to augment antidepressants.
This section provides psychiatric NPs with a clear understanding of when and how to use these secondary options strategically. It covers indications, mechanisms of action, off-label uses, and safety profiles—empowering you to fine-tune treatment plans, especially in complex or partial-response cases. With the right supporting cast, even stubborn symptoms can be managed more effectively.

